Defining masks for solvent flattening

• Molecular replacement: mask around atoms

• Experimental phases: Wang map or local rms map

  • protein regions have greater excursions from mean density than solvent regions

• Wang: truncate negative density
  compute mean density in sphere

• Local rms: deviations from mean in sphere

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© 1999-2005 Randy J Read, University of Cambridge. All rights reserved.

Last updated: 7 June, 2005