Publications on Shiga-like toxin structures

Boodhoo, A., Read, R.J. & Brunton, J. "Crystallization and preliminary X-ray crystallographic analysis of verotoxin-1 B-subunit." J. Mol. Biol. 221: 729-731 (1991).

Stein, P.E., Boodhoo, A., Tyrrell, G.J., Brunton, J.L. & Read, R.J. "Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli." Nature 355: 748-750 (1992).

Sixma, T.K., Stein, P.E., Hol, W.G.J. & Read, R.J. "Comparison of the B-pentamers of heat-labile enterotoxin and verotoxin-1: Two structures with remarkable similarity and dissimilarity." Biochemistry 32: 191-198 (1993).

Hazes, B. & Read, R.J. "Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells." Biochemistry 36: 11051-11054 (1997).

Ling, H., Boodhoo, A., Hazes, B., Cummings, M.D., Armstrong, G.D., Brunton, J.L. & Read, R.J. "Structure of the Shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb₃." Biochemistry 37: 1777-1788 (1998).

Cummings, M.D., Ling, H., Armstrong, G.D., Brunton, J.L. & Read, R.J. "Modeling the cabohydrate-binding specificity of pig edema toxin." Biochemistry 37: 1789-1799 (1998).

Bast, D.J., Banerjee, L., Clark, C., Read, R.J. & Brunton, J.L. "The identification of three biologically relevant globotriaosylceramide receptor binding sites on the verotoxin 1 B subunit." Molecular Microbiology 32: 953-960 (1999).

Ling, H., Pannu, N.S., Boodhoo, A., Armstrong, G.D., Clark, C.G., Brunton, J.L. & Read, R.J. "A mutant Shiga-like toxin IIe bound to its receptor Gb₃: structure of a group II Shiga-like toxin with altered binding specificity." Structure 8: 253-264 (2000).

Kitov, P.I., Sadowska, J.M., Mulvey, G., Armstrong, G.D., Ling, H., Pannu, N.S., Read, R.J. & Bundle, D.R. "Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands." Nature 403: 669-672 (2000).