Lecture Topics
|
Basic concepts and practical aspects
|
| Overview of X-ray crystallography |
Randy Read |
9 November |
| Crystallisation: theory
and practice |
Airlie McCoy |
16 November |
| Basic diffraction
theory: waves, interference, reciprocal space |
Randy Read |
23 November |
| X-ray data collection:
indexing, strategy, processing |
Andrew Leslie |
30 November |
| The phase problem:
introduction to phasing methods |
Randy Read |
7 December |
| Introduction
to fitting, refinement and validation |
Randy Read |
14 December |
Advanced topics
|
| Advanced diffraction:
waves, interference and complex numbers |
Randy Read |
18 January |
| Advanced diffraction:
atoms, crystals and reciprocal space |
Randy Read |
25 January |
| X-ray sources: from generators to synchrotrons |
Gwyndaf Evans |
8 February |
| Data collection, processing, complications |
Andrew Leslie |
15 February |
| Fourier transforms: structure
factors, phases and electron density |
Randy Read |
22 February |
| The convolution
theorem and its applications |
Randy Read |
29 February |
| Symmetry in real and reciprocal space |
Anne Bloomer |
7 March |
| The Patterson function and its implications |
Phil Evans |
28 March |
| Structure factor
statistics: Wilson statistics, SIGMAA... |
Randy Read |
4 April |
| Maximum likelihood:
theory, and application to structure refinement |
Randy Read |
11 April |
| Molecular replacement |
Randy Read |
18 April |
| Isomorphous replacement |
Randy Read |
25 April |
| Experimental phasing
by maximum likelihood |
Randy Read |
not presented |
| Anomalous scattering and MAD |
Gwyndaf Evans |
2 May |
| Density modification: theory
and practice |
Randy Read |
9 May |
| Fitting, refinement
and validation |
Phil Evans |
16 May |
| Analysing protein structures |
Arthur Lesk |
23 May |
